111SKIN

Luxury innovative skincare created by Dr Alexandrides of Harley St. Using patented NAC Y²™ with 20+ years of research for scientifically proven ingredients.

111SKIN is a luxury skincare brand founded by Dr Yannis Alexandrides of Harley Street, combining clinical expertise with patented NAC Y²™ technology backed by 20+ years of research. The collection spans sheet masks, serums, moisturisers, and treatment tools designed to optimise skin health and address visible signs of ageing.

Who Is 111SKIN and What They Offer

111SKIN is a doctor-led luxury skincare brand created by Dr Yannis Alexandrides, a renowned clinician at 111 Harley Street in London. The brand bridges the gap between professional clinical treatments and at-home skincare by translating surgical precision and medical skin science into consumer products. Every formula is informed by Dr Alexandrides' deep understanding of the skin's three-dimensional repair process. The brand positions itself as a pioneer in medical skincare innovation, using patented NAC Y²™ technology developed over two decades of research. Products are designed to work both as standalone routines and as complements to professional treatments, helping to optimise skin health, address visible ageing, and support pre- and post-surgical skin recovery. 111SKIN emphasises that their approach goes beyond traditional moisturisers and serums—they frame skincare as part of a holistic 360-degree skin health philosophy that includes experiential treatments and lifestyle guidance.

Product Categories and What's Available

111SKIN's collection is organised into eight main product categories, each serving a specific skincare need. Sheet masks form a substantial part of their range, offering targeted treatment options for intensive care routines. Moisturisers provide hydration and skin barrier support in multiple formulations. Serums and boosters deliver concentrated active ingredients designed to address specific concerns like firming, brightening, or hydration. Cleansers form the foundation of daily routines, while their tool range includes devices and applicators that enhance product efficacy. The brand also offers gift sets curated for various skin concerns or as introduction points to their system. Sample sizes are available for those wanting to trial products before committing to full sizes. This diversity means whether you're building a complete routine or targeting a specific skin concern, 111SKIN has products at different price points and delivery methods to suit various preferences and budgets.

What stands out

• Doctor-formulated with 20+ years of research backing each product
• Targets visible ageing and skin health with surgical precision approach
• Wide price range from entry-level samples to premium treatment systems

Worth knowing

• Luxury positioning means most products sit in higher price brackets
• Large collection may require time to identify which products suit your needs

What is NAC Y²™ and why does 111SKIN use it?

NAC Y²™ is a patented ingredient technology developed through over 20 years of research by founder Dr Yannis Alexandrides. It forms the scientific backbone of 111SKIN formulas, designed to deliver visible, targeted results in addressing skin concerns like ageing and firmness.

Are 111SKIN products suitable for post-surgical skin recovery?

Yes. The products are specifically designed to complement and support pre- and post-surgical skin recovery. Dr Alexandrides' clinical background means formulas align with surgical precision protocols, making them ideal for those undergoing or recovering from professional skin treatments.